Leukotriene
Leukotriene Leukotrienes are autocrine and paracrine eicosanoid lipid ... 5-lipoxygenase. History and name The name leukotriene comes from the words leukocyte and triene ... double bonds). What would be later named leukotriene C, "slow reaction smooth muscle-stimulating substance ... which converts it in two steps to leukotriene A4, an unstable epoxide. In cells equipped ... LTA4 is converted to the dihydroxy acid leukotriene LTB4, which is a powerful chemoattractant ...
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Category:Leukotriene antagonists
Category:Leukotriene antagonists Inhibitors of leukotriene action in asthma. Main members are montelukast and zafirlukast. Pages in category "Leukotriene antagonists" There are 2 pages in this ...
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Category:Leukotriene pathway inhibitors
Category:Leukotriene pathway inhibitors Leukotriene pathway inhibitors - presently only zileuton as member - used in asthma Pages in category "Leukotriene pathway inhibitors" There is 1 page in ...
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Eicosanoid
... 5-HPETE), and then 5-HPETE into leukotriene A4 (LTA4). LTA4 may be converted into LTB4 by the enzyme leukotriene A4 epoxide hydrolase. Eosinophils, mast cells, and alveolar macrophages use the enzyme leukotriene C4 synthase to conjugate glutathione with LTA4 to make leukotriene C4 (LTC4). LTC4 is transported out of ... moiety is removed from it to make leukotriene D4 (LTD4). LTD4 is cleaved by ...
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Leukotrien   (translated from German)
Leukotrien Leukotriene became in Leukocytes (white blood corpuscles) discovered ... parent compound for the biosynthesis of various Leukotriene. The group of substances is divided into the Peptido (Cysteinyl)Leukotriene LTC4, LTD4 and LTE4 and that Cysteinylfree LTB4. The formation of the Leukotriene in the body is made by the ...
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User:Spaully/WIP Asthma
... low-dose inhaled glucocorticoids—or alternatively, an oral leukotriene modifier, a mast-cell stabilizer, or theophylline—may ... 2 agonist may be prescribed; alternatively, a leukotriene modifier or theophylline may substitute for the ... fluticasone, budesonide, beclomethasone, mometasone , flunisolide, and triamcinolone). Leukotriene modifiers (montelukast, zafirlukast, pranlukast , and zileuton). Mast ...
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Montelukast
Montelukast Montelukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment ... albuterol inhaler. Montelukast blocks the action of leukotriene D4 on the cysteinyl leukotriene receptor CysLT 1 , thus inhibiting bronchoconstriction. hhhhh ...
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Mast cell
... newly formed lipid mediators (eicosanoids) prostaglandin D2 leukotriene C4 cytokines Histamine dilates blood vessels, makes ... preventing release of histamine and related mediators. Leukotriene antagonists (such as montelukast and zafirlukast) block the action of leukotriene mediators, and are being used increasingly in ...
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Asthma
... low-dose inhaled glucocorticoids—or alternatively, an oral leukotriene modifier, a mast-cell stabilizer, or theophylline—may ... 2 agonist may be prescribed; alternatively, a leukotriene modifier or theophylline may substitute for the ... fluticasone, budesonide, beclomethasone, mometasone , flunisolide, and triamcinolone). Leukotriene modifiers (montelukast, zafirlukast, pranlukast , and zileuton). Mast ...
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Montelukast   (translated from German)
... that it prevents, that determined itself Hormones ( Leukotriene ) in their respective connection place in the ... the breath ways. The effects of the Leukotriene regarding reinforcement of inflammation procedures and increased ...
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