Prodrug
Prodrug A prodrug is a pharmacological substance (drug) which is ... significantly less active) form. Once administered, the prodrug is metabolised in the body (in vivo ... The rationale behind the use of a prodrug is generally for ADME optimization. Prodrugs are ... bioavailability. However, sometimes the use of a prodrug is unintentional, especially in the case ...
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Prodrug   (translated from German)
Prodrug Prodrug a medicine, which is even not effective ... substance verstoffwechselt becomes. An example of a Prodrug is Levodopa to the treatment that Parkinson ...
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Fosinopril   (translated from German)
... Herzinsuffizienz one uses. Fosinopril is an inactive Prodrug . Its effect principle is based after activation ... one Phosphate structure. Fosinopril is an inactive Prodrug, which through Veresterung and Acetalbildung became. The ...
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Ramipril   (translated from German)
... uses. IST ein inaktives van Ramipril selbst Prodrug . Its effect principle is based after activation ... Alanin and Phenylalanin . Ramipril is an inactive Prodrug, which through Veresterung the free Carbonic acid ...
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Enalapril   (translated from German)
... Herzinsuffizienz one uses. Enalapril is an inactive Prodrug . Its effect principle is based after activation ... as from Phenylbuttersaeureethylester. Enalapril is an inactive Prodrug, which through Veresterung the free Carbonic acid ...
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Valganciclovir
... ester of ganciclovir, it is actually a prodrug for ganciclovir. After oral administration, it is ... et al. Transport of valganciclovir, a ganciclovir prodrug, via peptide transporters PEPT1 and PEPT2. J ...
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Fosphenytoin
... Holding France) is a water-soluble phenytoin prodrug used only in hospitals for the treatment ... limited. One solution was to develop a prodrug that did not have these drawbacks. Fosphenytoin ...
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Talk:Heroin
... deacetylation into morphine in the brain (see prodrug). The main difference is in heroin's ... newer research, heroin isn't only a prodrug because also the heroin itself docks on ...
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Experimental cancer treatment
... enzyme that can convert a non-toxic prodrug into a toxic drug. With the proliferation ... in the tumour. Thus a systemically applied prodrug is metabolised to the toxic drug only ...
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Oseltamivir   (translated from Spanish)
... under the mark Tamiflu. Oseltamivir is a prodrug, that is transformed into an active compound ... more superior to the one of the prodrug, oseltamivir. The conversion of oseltamivir to the ...
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