WRN (gene)
WRN (gene) WRN (Werner syndrome) is a human gene that provides instructions for producing Werner protein ... critical for making a blueprint of a gene for protein production, a process called ...
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Talk:WRN (gene)
Talk:WRN (gene) Some text in this article was taken from http://ghr.nlm.nih.gov/gene=wrn (public domain)
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WRN
WRN WRN is a three-letter abbreviation with multiple meanings, as described below: WRN, the gene responsible for Werner syndrome. The UK railway ...
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Werner syndrome
... of Progeria. The defect is on a gene that codes DNA helicase and it is ... 40,000 people. Genetics In 1996 the gene responsible for Werner syndrome was identified (and named WRN) and found to be a member of ... the genes responsible for Bloom syndrome (BLM gene), and a subset of Rothmund-Thomson (RECQ4 gene) patients. The Werner protein is thought ...
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Category:Genes
... of notable genes A ABCA12 ACADM APC (gene) ASL (gene) ASPM ASS (gene) ATP7A Abl gene Antennapedia B BTD Basic-helix-loop-helix Bcl-2 C CCR5 CFTR (gene) COL11A2 COL1A1 COL2A1 Cdx2 D DCDC2 ...
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Genetic counseling: Osteosarcoma and Li-Fraumeni Syndrome (Psychology wiki)
... Genetic Etiology Due to mutation in TP53 gene on 17p13 that codes for TP53 protein ... more than 50% of cases Tumor suppressor gene nicknamed "guardian of the genome" Acts as ... cell cycle by mediating RB pathway CHEK2 gene at 22q12.1 also associated with Li ... few families thus far Putative tumor suppressor gene Lies in TP53 pathway One of checkpoint ... due to TP53 mutations Mutations in this gene appear to be most common in ...
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RecQ helicase
... responsible for several disorders: Bloom syndrome: BLM gene Rothmund-Thompson's syndrome: RECQ4 gene Werner syndrome: WRN gene External links RecQ Helicases, introduction at UNC's Selsky Lab. BLM gene encodes a RecQ Helicase, descripton of ...
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Rothmund-Thompson's syndrome
... by a mutation in the RecQ helicase gene RECQ4, which is involved in DNA replication ... RecQ helicase defects are: Bloom syndrome: BLM gene Werner syndrome: WRN gene External links RecQ Helicases, introduction at UNC's Selsky Lab. BLM gene encodes a RecQ Helicase, descripton of ...
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ウェルナー syndrome   (translated from Japanese)
... inferior hereditary disease, the person 8th chromosome WRN With the single unit which is called gene is cause. Role of this gene is not elucidated yet completely, but it ... protein and participate in the maintenance and gene restoration of stability of the chromosome it ...
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テロメア   (translated from Japanese)
... that time Morgan and others, the chromosome gene , but DNA is the heredity substance. Terminal ... DNA 切断を感知・修復するものなどが含まれており、細胞の状態に応じて、これらのタンパク質複合体の組成や酵素活性が変化することで、テロメアの制御を行っていると考えられている。 D-ループには Pot1 と呼ばれるタンパク質（図の黄色の丸）が結合して安定化させており、これがT-ループの形成と保護に関与すると考えられている。ヒトの早老症ウェルナー症候群の原因遺伝子 WRN は D-ループ形成に機能するようである。また、TRF と呼ばれるタンパク質がループした二本鎖 DNA 部分に結合しており、これを介して他のタンパク質がテロメアに結合している。 姉妹染色分体のテロメアどうしを結びつけておくタンパク質もあり、細胞周期のM期（分裂期）に異常な染色体分配が生じないよう抑制する機能を担っていることがわかりつつある。このタンパク質はセントロメアや腕部の接着に機能するコヒーシンとは異なるものである。 ...
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